EWOT stands for Exercise With Oxygen Therapy. It is a structured practice where you perform cardiovascular exercise — cycling, walking, or using an elliptical — while breathing 93% concentrated oxygen through a sealed mask connected to a large oxygen reservoir.
During exercise, your heart rate
rises, blood vessels dilate, and breathing rate increases dramatically. EWOT takes advantage of this window of peak demand by delivering oxygen-enriched air when your body is already primed to absorb and distribute it. The
result is improved oxygen delivery to working tissue, enhanced ATP production in the mitochondria, and support for circulation, energy, and recovery.
A complete EWOT system includes an
oxygen concentrator, a 1,000-liter reservoir, a sealed exercise mask, and
tubing — everything needed for repeatable 15-minute sessions at home or in a clinical environment.
Unlike passive oxygen therapy
performed at rest, EWOT pairs oxygen with the physiological changes of exercise. That timing is what makes different from simply breathing supplemental oxygen.
Turn on the oxygen concentrator and let the 1,000-liter reservoir fill. A 10 LPM system fills in approximately 90 minutes. A 5 LPM system fills in about 3 hours. Many users set an outlet timer or smart plug to automate this step so the reservoir is ready when they are. The concentrator pulls in room air and outputs approximately 93% oxygen — no tanks to refill or replace.
Put on the sealed EWOT mask, step onto your bike, treadmill, or elliptical, and exercise for 15 minutes while breathing 93% concentrated oxygen. Start at a comfortable pace and gradually work up to 70–80% of
your max heart rate over time. The session doesn't need to be intense — even moderate movement at an elevated heart rate creates the circulation and oxygen demand that make EWOT effective.
After 15 minutes, remove the mask and continue your day. Most users report feeling energized and clear-headed immediately after a session. Consistent use — 3 to 5 sessions per week — produces the strongest and most sustained results. Many people notice improvements in energy and
recovery within the first one to two weeks of regular sessions.
Each system includes an oxygen concentrator, a 1,000-liter reservoir, a sealed NextGen exercise mask, tubing, and all connection hardware. The difference between systems is refill speed and intended usage volume — not the core therapy. Both deliver 93% oxygen for structured 15-minute sessions.
EWOT is used by athletes, biohackers, and people managing chronic health conditions — from weekend runners to
people recovering from Lyme disease, long COVID, and autoimmune challenges.

Endurance support, faster recovery, improved VO2 max. Exercise with Oxygen Therapy is used by competitive athletes, CrossFit practitioners, and runners to remove oxygen as the performance limiter.

Mitochondrial energy production, circulation support, and cellular resilience. EWOT fits into daily wellness routines alongside red light therapy, cold exposure, and other optimization tools.

People navigating Lyme disease, long COVID, chronic fatigue, and inflammatory conditions use EWOT to support oxygen delivery and energy production as part of a broader recovery strategy.
Brad Pitzele explains how EWOT systems deliver concentrated oxygen during exercise and why timing matters more than concentration alone.
I didn't set out to start a wellness company. I was trying to recover my health. After being diagnosed with Lyme disease, cancer, and autoimmune conditions, I used EWOT as a core part of my recovery. What I learned was simple: when the body has the oxygen and energy it needs, it can repair, detoxify, and regenerate.
One Thousand Roads exists because I needed systems that actually worked — and I couldn't find them. Every system we sell is the same EWOT system I use myself.
"I built this company after using EWOT to recover from Lyme disease, cancer, and autoimmune illness. Its the same system I use myself."

Some people start with EWOT alone. Others combine it with red light therapy from the start —
using EWOT first to flood the body with oxygen, then using targeted red and near-infrared light to stimulate the mitochondria to utilize that excess oxygen. We call this the Oxygen Synergy System.
It is designed as a coordinated protocol, not separate purchases used independently.
Learn How EWOT + Red Light Work Together
Explore Oxygen Synergy SystemsWe publish in-depth guides on EWOT benefits, safety, protocols, comparisons, and condition-specific applications. Our EWOT research page compiles primary-source citations and clinical study summaries supporting EWOT mechanisms — including a double-blind study showing a 17% improvement in oxygenation state after just two 15-minute sessions, and research demonstrating that 88% of patients with exercise-induced low blood oxygen improved with EWOT.
EWOT Education HubEWOT and HBOT both increase oxygen availability, but they work differently. HBOT uses a pressurized chamber to force oxygen into tissue while you sit or lie still. Sessions typically last 60–90 minutes, require a prescription, and often cost $100–$300 per session at a clinic. EWOT uses cardiovascular exercise to increase circulation and oxygen demand, then delivers 93% concentrated oxygen during that window of peak demand. Sessions take 15 minutes, can be done at home with your own system, and do not require a prescription. Many people explore both options — for a detailed breakdown, read our EWOT vs HBOT comparison guide.
Yes. Our EWOT systems are specifically designed for home use. Setup takes about 15 minutes — the system plugs into a standard wall outlet and requires no professional installation, no permanent modifications to your space, and no ongoing tank deliveries. The oxygen concentrator produces its own oxygen from room air. Most users complete their first session the same day their system arrives. Read the EWOT at Home Guide
EWOT delivers 93% oxygen — the same concentration used in standard home oxygen concentrators — during controlled 15-minute exercise sessions. It does not involve pressurized environments, medical-grade equipment, or oxygen tanks. The primary consideration is exercise intensity: we recommend starting at a comfortable pace and gradually increasing over time, especially if you are recovering from a chronic condition. Over 90% of users experience no adverse effects. For a detailed review of safety considerations, potential side effects, and who should consult a doctor before starting, read our EWOT Safety Guide
A standard EWOT session is 15 minutes of cardiovascular exercise — cycling, walking on a treadmill, or using an elliptical — while breathing 93% concentrated oxygen through a sealed mask connected to a reservoir. Most people start at a comfortable intensity and gradually work up to 70–80% of their theoretical max heart rate over time. Sessions are typically done 3 to 5 times per week. The protocol can be adjusted for different fitness levels and health situations. For the full breakdown including ramp-up guidance for sensitive users, read our EWOT Protocol Guide
Complete EWOT systems from One Thousand Roads start at $1,899.99 for a 5 LPM system and $2,499.99 for a 10 LPM system. Both include the oxygen concentrator, 1,000-liter reservoir, sealed NextGen exercise mask, tubing, and all connection hardware. Free shipping is included on all US orders. The difference between systems is refill speed and intended usage volume — not the therapy itself. Both deliver the same 93% oxygen for the same 15-minute sessions. Most individual home users choose the 5 LPM system. Households with multiple users, or anyone who wants more scheduling flexibility, typically choose the 10 LPM.
Compare EWOT Systems
If you have questions about which system is right for you, or whether EWOT fits your situation, we're here to help.
Explore EWOT Systems