Research on the Benefits of EWOT
Anti-Aging EWOT Research
Aging is characterized by a general decrease in O2 supply to tissues and a reduction in tissue pO2. A diminished vascularization in aging alters the diffusion of O2 at the capillary tissue level.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4543034/
Aging is associated with both hypoxia (38% reduction in oxygen levels, Po2 21.7 mmHg) and increases reactive oxygen species in visceral fat depots of aging male C57Bl/6 mice.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275102/
In a clinical examination of 46 patients with EWOT, about 2/3 experienced an increase of resting values of arterial oxygen pressure. This effect continues more than 3 months after the end of O2MT [EWOT], demonstrating prophylactic and therapeutic effects, including improvement of cardiorespiratory and cardiovascular efficiency, especially for the use of preventive-treatment and gerontology-therapy.
https://www.ncbi.nlm.nih.gov/pubmed/7222733
Double-blind study on 20 male healthy volunteers from the working population showed a 17% improvement of the energetic or oxygenation state of the subjects two-weeks after the completion of two 15-minute EWOT sessions.
https://www.ncbi.nlm.nih.gov/pubmed/6711017
The beneficial effects of EWOT can persist for weeks, months or even years.
https://www.ncbi.nlm.nih.gov/pubmed/6475110
Long COVID EWOT Research
30 individuals with Long COVID that completed a 6 week, twice supervised rehabilitation program improved their exercise capacity, respiratory symptoms, fatigue and cognition. Endurance increased by 186%, fatigue improved 17%, and cognition scores improving from a range considered indicative of mild-cognitive-impairment to near-normal.
https://journals.sagepub.com/doi/full/10.1177/14799731211015691
88% of patients with exercise-induced low blood oxygen levels improved with EWOT - including improved endurance time, oxygen saturation, reduced shortness of breath, and reduction in leg fatigue.
https://onlinelibrary.wiley.com/doi/10.1111/resp.14176#.YYPu2HJNRLg.twitter
43% of recovered COVID patients had oxygen desaturation during a 6-minute walking test.
https://www.sciencedirect.com/science/article/pii/S2531043721001173
Researchers at the University of Dayton & Pulmonary Wellness Foundation are studying EWOT to improve outcomes of people with Long COVID. "By quieting these inflammatory responses using both exercise and supplemental oxygen, we are seeing people’s exercise tolerance and symptom burden improving and in many cases resolving completely."
https://www.wvxu.org/health/2021-03-01/researchers-studying-exercise-for-covid-long-haulers
Most common Long COVID symptoms include fatigue (47%), shortness of breath (32%), muscle pain(25%), joint pain(20%), and headaches (18%).
https://journals.sagepub.com/doi/full/10.1177/01410768211032850
77% of participants with Long COVID Brain fog had abnormalities in their cerebrospinal fluid due to an increase in inflammation.
https://onlinelibrary.wiley.com/doi/full/10.1002/acn3.51498
EWOT Research on Cancer, Inflammation & the Immune System
Over 70 years ago, Warburg showed that cells could always be made cancerous by subjecting them to periods of hypoxia.
https://www.ncbi.nlm.nih.gov/pubmed/17656037
In metastatic cells, the accelerated cell proliferation will further increase the level of hypoxia due to the increased cell accumulation, potentially forming a vicious cycle.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493170/
Higher oxygen status of a tumor correlates to higher survival rate: 22 patients with nonmetastatic, high-grade, soft tissue sarcomas underwent preoperative irradiation and hyperthermia and pretreatment measurement of tumor oxygenation. The 18-month actuarial disease-free survival was 70% for patients with tumor median oxygen pressure (pO2) values of >10 mm Hg but only 35% for those with median pO2 values of < 10 mm Hg (P = 0.01). Median pO2 was 7.5 mm Hg for metastasizing tumors versus 20 mm Hg for non-metastasizing tumors (P = 0.03).
http://cancerres.aacrjournals.org/content/56/5/941
With the 15-minute EWOT sessions and desiccated thymus pills, precancerous skin lesions were unprimed within 10 months.
https://www.ncbi.nlm.nih.gov/pubmed/4049925
Hypoxia can induce inflammation. In persons with mountain sickness, for example, levels of circulating proinflammatory cytokines increase, and vascular leakage causes pulmonary or cerebral edema.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930928/
Hypoxia and inflammation are two sides of the same coin.
http://www.pnas.org/content/110/46/18351
EWOT Research on Athletic Performance
Several studies show the many benefits of EWOT:
- Endurance increased by 32-67%
- Power increased by 8-14%
- VO2 Max increased by 4-12%
- Lactic acid: reduced 34-60%
- Fat-burn for fuel increased
- Mitochondrial capacity maximized
- Reaction time reduced 12-18%
- Short-term memory improved 19-23%
- Recovery time: reduced 27%
https://www.onethousandroads.com/pages/ewot-research
https://www.ncbi.nlm.nih.gov/pubmed/16015135
https://www.ncbi.nlm.nih.gov/pubmed/10066722
https://www.ncbi.nlm.nih.gov/pubmed/8252958
https://www.ncbi.nlm.nih.gov/pubmed/1396641
https://www.ncbi.nlm.nih.gov/pubmed/11581334
https://www.ncbi.nlm.nih.gov/pubmed/16403777
https://www.ncbi.nlm.nih.gov/pubmed/895429
https://www.ncbi.nlm.nih.gov/pubmed/6752626
https://www.ncbi.nlm.nih.gov/pubmed/10409591
https://www.ncbi.nlm.nih.gov/pubmed/2711706
https://www.ncbi.nlm.nih.gov/pubmed/21120743
Benefits of Exercise on Oxygen Consumption
EWOT leverages the phsyiological changes of exercise to deliver up to 14 hours of oxygen in a 15-minute session. We are able to do this by leveraging the powerful physiological changes that occure during exercise, including:
- 4x increase in respiration rate
- 8x increase in breathing volume (tidal volume)
- Thinning lung-blood membrane to allow more gas exchange
- 20x increase in lung-blood gas exchange
- 700% increase in blood flow due to increased heart rate and stroke volume
- Vasodilation - increased diameter in blodd vessels
- 60% - 90% increase in systolic blood pressure - which drives oxygen deeper into tissues