Education Hub EWOT Education Research

The Research on Oxygen and EWOT

Why the oxygen level inside your tissue matters — and what happens when you raise it.

Last updated: August 2026

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Exercise With Oxygen Therapy (EWOT) is exercise done while breathing high-concentration oxygen instead of ordinary room air, which is only 21% oxygen. Our EWOT systems are built to run these sessions at home.

Aging

10% drop in your body's oxygen consumption every decade after 30 - Link

Cellular energy production declines with age - Link

Lower oxygen drives measurably worse thinking - Link

Older brains receive less oxygen than they demand - Link

2 out of 3 patients had higher resting arterial oxygen levels after EWOT — still measurable more than 3 months later - Link


Inflammation

Low oxygen causes inflammation - Link

Arthritic joints are oxygen-starved (hypoxic) — and the lower the oxygen, the worse the inflammation - Link

Oxygen-starved joints showed more tissue damage - Link

Oxygen starvation and inflammation are two sides of the same coin - Link

Mitochondria and Cellular Energy

33% more ATP production with EWOT in patients with damaged mitochondria - Link

Oxygen delivery — not your mitochondria — is what caps energy production - Link

Cancer

the survival rate at 18 months in tumors with higher oxygen status - Link

Tumor oxygen level: a top predictor of survival - Link

Low oxygen causes tumors to spread - Link

Oxygen starvation drives cancer to spread - Link

Nobel laureate Otto Warburg found he could turn a normal cell into a cancer cell by starving it of oxygen - Link

PET scans find cancer by detecting the broken oxygen metabolism Warburg described - Link


When Illness Is What Limits Your Exercise

15% lower perceived effort - Link

8% more power output - Link

118% longer endurance with pulmonary vascular disease - Link

60% longer endurance with COPD - Link

2× greater gains in peak exercise capacity after six weeks of EWOT in COPD - Link

38% longer endurance - Link

17% better physical capacity - Link

Long COVID

54% better exercise tolerance after EWOT protocol - Link

University of Dayton and the Pulmonary Wellness Foundation are studying EWOT for Long COVID - Link

77% of Long COVID brain fog patients had inflammation markers in their spinal fluid - Link

43% of "recovered" COVID patients drop their blood oxygen during a six-minute walk - Link

47% of Long COVID patients report fatigue, the most common symptom - Link

Brain and Mental Performance

19–23% more information processing capacity - Link

12–18% faster reaction time - Link

Athletic Performance

41% longer time to exhaustion - Link

17% more power during exercise - Link

10% higher VO₂ max - Link

6% higher peak power output - Link

6% faster time-trial performance - Link

56% less lactate production during exercise - Link

52% more fat burned for fuel during exercise - Link

16% more reps before muscle fatigue - Link

15% more sprints before exhaustion - Link

14% more total work during repeated sprints - Link

14% better muscle-strength recovery after exercise - Link

65% greater endurance gains - Link

8% more power output after six weeks of EWOT - Link

Higher oxygen concentrations produced greater performance gains - Link

How EWOT Delivers More Oxygen

more oxygen dissolved directly into your blood plasma - Link

20× more air through your lungs per minute during exercise - Link

4–5× more blood pumped per minute during exercise - Link

20× more blood flow into working muscle through vasodilation — the widening of your blood vessels - Link

28% higher systolic blood pressure during exercise — pressure that drives oxygen deeper into tissue - Link


EWOT Systems

Complete home systems for 15-minute daily sessions

Concentrator, reservoir, and mask built to hold a high oxygen concentration through a full session.

Explore Systems →

Note

This page links to published studies for educational purposes. It does not make claims regarding the diagnosis, treatment, cure, or prevention of any disease. These statements have not been evaluated by the Food and Drug Administration. EWOT is not a substitute for medical care. If you have a heart, lung, or circulatory condition, are undergoing cancer treatment, or are managing any chronic illness, talk with your physician before beginning any exercise or oxygen program.

Related: EWOT Education · Red Light Therapy Education · Education Hub